Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402013 | 0.86 | BCAT2 (0.56) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL7524098 | 0.85 | BCAT2 (0.46) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL5608858 | 0.84 | BCAT2 (0.61) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL1286522 | 0.82 | KEAP1 (0.41) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL901580 | 0.79 | BCAT2 (0.71) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL3453140 | 0.79 | KDM4E (0.61) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL5742619 | 0.78 | MYC (0.53) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL28309606 | 0.77 | KEAP1 (0.44) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL466296 | 0.77 | KDM4E (0.54) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E | |
| SCHEMBL8910680 | 0.76 | KDM4E (0.51) | KEAP1NFE2L2BCAT2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719238-A | ADDING A MINOR AMOUNT OF ARAMIDE POWDER | SHELL OIL COMPANY (US) | 1998-02-17 | — | — | US | claimed |