Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284288 | 0.83 | BCAT2 (0.47) | KEAP1NFE2L2HSD17B10BCAT2PDK2 | |
| SCHEMBL8675281 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2HSD17B10BCAT2PDK2 | |
| SCHEMBL402013 | 0.79 | BCAT2 (0.56) | KEAP1NFE2L2HSD17B10BCAT2PDK2 | |
| SCHEMBL7524098 | 0.75 | BCAT2 (0.46) | KEAP1NFE2L2BCAT2PDK2PARP1 | |
| SCHEMBL28309606 | 0.74 | KEAP1 (0.44) | KEAP1NFE2L2BCAT2PDK2PARP1 | |
| SCHEMBL5608858 | 0.74 | BCAT2 (0.61) | KEAP1NFE2L2HSD17B10BCAT2PDK2 | |
| SCHEMBL28442421 | 0.72 | SLC6A2 (0.46) | KEAP1NFE2L2BCAT2PARP1KDM4E | |
| SCHEMBL466296 | 0.71 | KDM4E (0.54) | KEAP1NFE2L2HSD17B10BCAT2PARP1 | |
| SCHEMBL8910680 | 0.70 | KDM4E (0.51) | KEAP1NFE2L2HSD17B10BCAT2PARP1 | |
| SCHEMBL901580 | 0.69 | BCAT2 (0.71) | KEAP1NFE2L2HSD17B10BCAT2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622265-A | COPOLYAMIDES | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1986-11-11 | — | — | US | claimed |
| US-8674134-B2 | Oligomer functionalized nanotubes and composites formed therewith | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120088934-A1 | OLIGOMER FUNCTIONALIZED NANOTUBES AND COMPOSITES FORMED THEREWITH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-12 | — | — | US | disclosed |
| EP-0329591-B1 | PNEUMATIC TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-07-14 | — | — | EP | disclosed |
| EP-0296093-B1 | PNEUMATIC TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |
| EP-0329591-A2 | Pneumatic tires | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4832102-A | Pneumatic tires | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| US-4832103-A | Pneumatic tire having plural aramid carcass plies | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-05-23 | — | — | US | disclosed |
| US-4622265-A | COPOLYAMIDES | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1986-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088934-A1 | OLIGOMER FUNCTIONALIZED NANOTUBES AND COMPOSITES FORMED THEREWITH | TNS4, ILK, PFAS | KEAP1 2863/4885NFE2L2 3259/4885HSD17B10 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.