Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675205 | 0.87 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL8324213 | 0.84 | PTGER1 (0.80) | PTGER1PTGER4PTGER3PTGER2PTGES | |
| SCHEMBL8675521 | 0.84 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL301122 | 0.83 | ALDH1A1 (0.69) | ALDH1A1KMT2APTK2BTP53HTT | |
| SCHEMBL20162476 | 0.83 | FOLH1 (0.61) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL8677422 | 0.83 | PTGER1 (0.65) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 | |
| SCHEMBL2446724 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KMT2APTK2BHTT | |
| SCHEMBL8531492 | 0.80 | LMNA (0.61) | ALDH1A1KMT2A | |
| SCHEMBL8698803 | 0.80 | FOLH1 (0.58) | ALDH1A1KMT2AFOLH1HTT | |
| SCHEMBL11710027 | 0.80 | FOLH1 (0.61) | PTGER1PTGER4PTGER3PTGER2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811459-A | PAIN RELIEVERS | ZENECA LIMITED (GB) | 1998-09-22 | — | — | US | disclosed |