Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801627 | 0.89 | FNTA (0.45) | OXTRCCKBR | |
| SCHEMBL8801536 | 0.83 | OXTR (0.45) | OXTRCCKBR | |
| SCHEMBL8674482 | 0.81 | LMNA (0.44) | CCKBR | |
| SCHEMBL8677103 | 0.81 | CCKBR (0.42) | OXTRCCKBR | |
| SCHEMBL8670555 | 0.79 | LMNA (0.44) | CCKBR | |
| SCHEMBL8801083 | 0.79 | OXTR (0.48) | OXTRCCKBR | |
| SCHEMBL8676259 | 0.79 | CCKBR (0.43) | CCKBR | |
| SCHEMBL8800205 | 0.78 | OXTR (0.51) | OXTRCCKBR | |
| SCHEMBL8801839 | 0.78 | CCKBR (0.50) | OXTRCCKBR | |
| SCHEMBL8674323 | 0.77 | LMNA (0.42) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | claimed |
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |