Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6557720 | 0.81 | GPR3 (0.34) | GPR3 | |
| Hydrochloric Acid SCHEMBL9165907 | 0.76 | MEN1 (0.33) | GPR3 | |
| SCHEMBL7634447 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7155172 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7565030 | 0.74 | PTPN1 (0.30) | — | |
| SCHEMBL1568290 | 0.74 | GPR3 (0.46) | GPR3 | |
| Hydrochloric Acid SCHEMBL29236432 | 0.74 | PTPN1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL6557718 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL9168451 | 0.72 | MEN1 (0.34) | GPR3 | |
| SCHEMBL7645025 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770663-A | HOMO OR COPOLYMERIZING UNSATURATED MONOMER SELECTED FROM ALPHA-OLEFIN IN PRESENCE OF METALLOCENE CATALYST AND A ORGANOMETALLIC COMPOUND OF 1A, 2A AND 3B AS COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1998-06-23 | — | — | US | disclosed |