SCHEMBL8682122

SCHEMBL8682122

OC1=CC=COC1c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA2 P00918 1/20 0.32
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
SLC6A3 Q01959 1/20 0.31
SIRT1 Q96EB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27766848 0.76 CA2 (0.32) KDM4EPOLBMAPTALDH1A1CA2
SCHEMBL28872911 0.76 SLC6A3 (0.38) KDM4EPOLBMAPTALDH1A1CA2
SCHEMBL9952030 0.76 CA2 (0.32) KDM4EPOLBMAPTALDH1A1CA2
SCHEMBL29153946 0.72 ALDH1A1 (0.31) ALDH1A1CA2TSHR
SCHEMBL7252825 0.63 ALDH1A1 (0.42) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL28463084 0.63
SCHEMBL29253910 0.61 KDM4E (0.45) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL4498488 0.61 KDM4E (0.50) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL29964241 0.60 TSHR (0.35) KDM4EPOLBMAPTALDH1A1KMT2A
SCHEMBL11237308 0.60 BACE1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736293-A USING MIXTURES OF 1-PHENYL-3-PYRAZOLIDONES AND CATECHOLS(AND DERIVATIVES) AS REDUCING AGENTS IN HEAT DEVELOPMENT OF A LAMINATED PHOTOSENSITIVE SHEET YIELDS HIGH DENSITY IMAGES HAVING LOW FOGGING, GOOD HALFTONES AND HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1998-04-07 US disclosed