SCHEMBL9952030

SCHEMBL9952030

CC1=CC=COC1c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CYP2C19 P33261 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28872911 0.76 SLC6A3 (0.38) CA2ALDH1A1TSHRRAB9ASLC6A3
SCHEMBL27766848 0.76 CA2 (0.32) CA2ALDH1A1TSHRRAB9ASLC6A3
SCHEMBL8682122 0.76 KDM4E (0.37) CA2ALDH1A1TSHRRAB9ASLC6A3
SCHEMBL29153946 0.72 ALDH1A1 (0.31) CA2ALDH1A1TSHR
SCHEMBL4658070 0.64
SCHEMBL29345313 0.64 MAOB (0.34) ALDH1A1SLC6A3CYP2C19KDM4E
SCHEMBL7252825 0.63 ALDH1A1 (0.42) CA2ALDH1A1TSHRRAB9ASLC6A3
SCHEMBL15614477 0.61 ALDH1A1 (0.38) ALDH1A1TSHRKDM4E
SCHEMBL29964241 0.60 TSHR (0.35) CA2ALDH1A1TSHRRAB9ASLC6A3
SCHEMBL29492629 0.60 TSHR (0.34) TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2654809-A1 METHOD FOR COUNTERACTING AMMONIA MALODOR Firmenich SA (CH) 2013-10-30 EP disclosed
WO-2012084916-A1 METHOD FOR COUNTERACTING AMMONIA MALODOR FIRMENICH SA (CH) 2012-06-28 WO disclosed