Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666854 | 0.90 | LMNA (0.37) | MEN1KMT2AMAPTLMNAPKM | |
| SCHEMBL8683956 | 0.88 | POLB (0.36) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8683766 | 0.88 | REN (0.38) | MEN1KMT2ALMNAALDH1A1POLB | |
| SCHEMBL8686069 | 0.86 | RAB9A (0.38) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8683686 | 0.85 | LMNA (0.38) | MEN1KMT2ALMNAPKMALDH1A1 | |
| SCHEMBL8684526 | 0.85 | CYP2C19 (0.43) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL8684409 | 0.81 | KAT6A (0.39) | LMNAHTTSMN1; SMN2PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL8684148 | 0.80 | KAT6A (0.38) | LMNAHTTSMN1; SMN2PKMALDH1A1 | |
| SCHEMBL8666356 | 0.75 | LMNA (0.41) | MEN1KMT2AMAPTLMNACYP3A4 | |
| SCHEMBL8666857 | 0.72 | KMT2A (0.38) | MEN1KMT2AMAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |