Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592750 | 0.83 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL8686911 | 0.76 | LMNA (0.47) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL8685809 | 0.76 | KDM4E (0.38) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A | |
| SCHEMBL10250830 | 0.74 | NCF1 (0.56) | NCF1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL28042011 | 0.71 | KDM4E (0.53) | NCF1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL439576 | 0.69 | NR4A2 (0.54) | NCF1ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL437139 | 0.69 | NCF1 (0.42) | NCF1ALDH1A1KMT2ANOS3NOS1 | |
| SCHEMBL436731 | 0.68 | KDM4E (0.56) | NCF1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL7618378 | 0.67 | CRHR1 (0.44) | NCF1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL25230625 | 0.67 | KDM4E (0.42) | ALDH1A1KDM4ESMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |