Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TPH1 | P17752 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686297 | 0.85 | L3MBTL1 (0.55) | ALDH1A1GAAMEN1KMT2AACHE | |
| SCHEMBL8682662 | 0.83 | ALDH1A1 (0.55) | ALDH1A1GAATDP1MEN1KMT2A | |
| SCHEMBL8686294 | 0.82 | MAPK8 (0.54) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL30049382 | 0.80 | GAA (0.74) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL153055 | 0.80 | GAA (0.74) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL27952523 | 0.78 | GAA (0.72) | ALDH1A1CA5AGAATDP1TSHR | |
| Hydrochloric Acid SCHEMBL2530820 | 0.78 | GAA (0.72) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL21328339 | 0.75 | CA5A (0.56) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL21328347 | 0.74 | CA5A (0.66) | ALDH1A1CA5AGAATDP1TSHR | |
| SCHEMBL21328344 | 0.74 | GAA (0.70) | ALDH1A1CA5AGAATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719187-A | Compounds having a guanidine structure and pharmaceutical composition containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 1998-02-17 | — | — | US | disclosed |
| US-5480884-A | Compounds having a guanidine structure | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0572635-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME. | CENTRE NAT RECH SCIENT (FR) | 1993-12-08 | — | — | EP | disclosed |
| EP-0572635-A4 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME. | CENTRE NAT RECH SCIENT (FR) | 1993-09-17 | — | — | EP | disclosed |
| WO-1993010102-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 1993-05-27 | — | — | WO | disclosed |