SCHEMBL8686381

SCHEMBL8686381

Cc1ccnc(Cl)c1-n1nn[nH]c1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.38
DHODH Q02127 1/20 0.31
DRD1 P21728 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8686695 0.84 PDE3B (0.33)
SCHEMBL8977225 0.77 ALDH1A1 (0.39)
SCHEMBL8598961 0.77 MAPK11 (0.39)
SCHEMBL8686369 0.76 ALDH1A1 (0.39)
SCHEMBL16490934 0.73 CSNK1A1 (0.33)
SCHEMBL8686970 0.72 LMNA (0.35) RXFP1
SCHEMBL8917531 0.71 ALDH1A1 (0.34)
SCHEMBL15352460 0.71 MAPK14 (0.40)
SCHEMBL8307466 0.71
SCHEMBL8600146 0.70 HCAR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1047777-C Pyridyl tetrazolinone derivatives, and preparation method, composition and application thereof BAYER AGROCHEM KK (JP) 1999-12-29 CN disclosed
CN-1224014-A Pyridyltetrazolinone derivatives BAYER AGROCHEM KK (JP) 1999-07-28 CN disclosed
US-5710278-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1998-01-20 US disclosed
US-5641727-A Herbicidal 1-pyridyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
CN-1121918-A 1-pyridyltetrazolinone derivatives BAYER AGROCHEM KK (JP) 1996-05-08 CN disclosed
EP-0692482-A2 1-pyridyltetrazolinone derivatives NIHON BAYER AGROCHEM K.K. (JP) 1996-01-17 EP disclosed