Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614088 | 0.83 | GAA (0.71) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL111479 | 0.76 | KMT2A (0.70) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL29543730 | 0.76 | KMT2A (0.70) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL184136 | 0.75 | ALDH1A1 (0.62) | KMT2AABCC1KDM4EPOLBHPGD | |
| Hydrochloric Acid SCHEMBL27870316 | 0.74 | KMT2A (0.50) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL10922018 | 0.74 | L3MBTL1 (0.69) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL233797 | 0.74 | KMT2A (0.57) | KMT2AABCC1KDM4EPOLBHPGD | |
| Benzene SCHEMBL27690342 | 0.74 | KMT2A (0.57) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL2968441 | 0.73 | KMT2A (0.66) | KMT2AABCC1KDM4EPOLBHPGD | |
| SCHEMBL6997869 | 0.73 | KMT2A (0.57) | KMT2AABCC1KDM4EPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719151-A | PHTHALAZINEDIONE COMPOUND; POLYMERASE INHIBITOR | SHALL SYDNEY (GB) | 1998-02-17 | — | — | US | disclosed |