Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686390 | 0.79 | AKR1B1 (0.41) | AKR1B1CGASMAOAMAOBCISD1 | |
| SCHEMBL8687692 | 0.75 | CGAS (0.42) | AKR1B1CGASMAOAMAOBCISD1 | |
| SCHEMBL8689993 | 0.73 | NLRP3 (0.49) | AKR1B1CGASPTPN1MAPTHTT | |
| SCHEMBL8688100 | 0.71 | ESRRA (0.44) | AKR1B1CGASPTPN1 | |
| SCHEMBL8686801 | 0.69 | TTR (0.63) | AKR1B1MAOAMAOBCISD1MEN1 | |
| SCHEMBL8685078 | 0.69 | TTR (0.63) | AKR1B1MAOAMAOBCISD1MEN1 | |
| SCHEMBL13780771 | 0.66 | MMP1 (0.54) | AKR1B1ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL24518535 | 0.65 | FFAR1 (0.56) | AKR1B1MAPTNPC1RAB9AHPGD | |
| SCHEMBL29727858 | 0.65 | FFAR1 (0.56) | AKR1B1MAPTNPC1RAB9AHPGD | |
| SCHEMBL10733983 | 0.65 | PRKCQ (0.54) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |