Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028316 | 0.81 | TSHR (0.51) | ALDH1A1TSHRCTSSCTSBCTSK | |
| SCHEMBL8690335 | 0.78 | CTSS (0.46) | ALDH1A1CTSSCTSBCTSKCTSL | |
| SCHEMBL7445242 | 0.74 | KMT2A (0.59) | ALDH1A1TSHRKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6450681 | 0.73 | KMT2A (0.40) | ALDH1A1TSHRCTSSCTSBCTSK | |
| SCHEMBL7412392 | 0.70 | ALDH1A1 (0.45) | ALDH1A1TSHRCTSSCTSKCTSL | |
| SCHEMBL7414172 | 0.69 | CTSL (0.67) | CTSSCTSBCTSKCTSLCTSH | |
| SCHEMBL7414175 | 0.69 | CTSL (0.67) | CTSSCTSBCTSKCTSLCTSH | |
| SCHEMBL7355925 | 0.69 | CTSL (0.64) | CTSSCTSBCTSKCTSLCTSH | |
| SCHEMBL8690341 | 0.68 | SSTR4 (0.39) | ALDH1A1CTSBCTSKCTSLCTSC | |
| SCHEMBL8691324 | 0.66 | CTSL (0.62) | CTSSCTSBCTSKCTSLCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |