Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.46 |
| ▸ | CTSB | P07858 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028324 | 0.81 | CTSL (0.51) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL8696240 | 0.80 | MMP2 (0.42) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL8696250 | 0.80 | MMP2 (0.42) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL8696245 | 0.80 | MMP2 (0.42) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7412388 | 0.79 | CTSS (0.42) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL8690337 | 0.78 | ALDH1A1 (0.47) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7378602 | 0.78 | CTSS (0.45) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7545314 | 0.74 | CTSS (0.62) | CTSSCTSBCTSLCTSC | |
| SCHEMBL7358325 | 0.74 | CTSL (0.62) | CTSSCTSBCTSLCTSKCTSH | |
| SCHEMBL7358323 | 0.74 | CTSL (0.62) | CTSSCTSBCTSLCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |