Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804733 | 1.00 | RAB9A (0.66) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL29941469 | 0.85 | NPC1 (0.67) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL6324872 | 0.85 | NPC1 (0.67) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL29804862 | 0.85 | RAB9A (0.71) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL3986163 | 0.85 | RAB9A (0.71) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL5053299 | 0.81 | NPC1 (0.87) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL10460032 | 0.80 | RAB9A (0.59) | RAB9ANPC1KDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL29363616 | 0.79 | NPC1 (1.00) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL28416625 | 0.79 | NPC1 (0.83) | RAB9ANPC1KDM4EMAPTMEN1 | |
| 2-Phenyl-1H-Indole SCHEMBL341378 | 0.79 | NPC1 (1.00) | RAB9ANPC1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272370-B | Synthesis method of trifluoromethyl substituted 3,3' -bis (2-phenylindolyl) methane compound | 福州大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110272370-A | A kind of synthetic method for 3,3 '-bis- (2-phenylindone base) methane compounds that trifluoromethyl replaces | 福州大学 | 2019-09-24 | — | — | CN | disclosed |
| US-8962558-B2 | Methods for reducing GnRH-positive tumor cell proliferation using the GnRH antagonist IN3 | VAN GROENINGHEN JOHANNES C (DE) | 2015-02-24 | — | — | US | disclosed |
| US-20120238494-A1 | METHODS FOR REDUCING GNRH-POSITIVE TUMOR CELL PROLIFERATION | VAN GROENINGHEN JOHANNES C (DE) | 2012-09-20 | — | — | US | disclosed |
| US-5849764-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 1998-12-15 | — | — | US | disclosed |
| US-5756507-A | TREATING SEX HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |