Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MPC2 | O95563 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687958 | 0.88 | PPARG (0.47) | KMT2AMEN1PPARGMAPTFFAR1 | |
| SCHEMBL8685503 | 0.83 | HTR6 (0.49) | PPARGMAPTFFAR1 | |
| SCHEMBL8685509 | 0.83 | POLB (0.50) | KMT2APPARGFFAR1NPSR1 | |
| SCHEMBL8813431 | 0.79 | MAPT (0.56) | KMT2APPARGMAPTFFAR1NPSR1 | |
| SCHEMBL8690487 | 0.79 | KMT2A (0.50) | KMT2AMEN1MAPTPLK1AKR1A1 | |
| SCHEMBL8811306 | 0.79 | RAB9A (0.51) | KMT2AMEN1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL8809908 | 0.79 | MAPT (0.40) | PPARGMAPTFFAR1NPSR1 | |
| SCHEMBL8810491 | 0.78 | PPARG (0.51) | PPARGMAPTFFAR1NPSR1 | |
| SCHEMBL8811662 | 0.78 | CHRNB2 (0.52) | PPARGMAPTFFAR1NPSR1 | |
| SCHEMBL8810577 | 0.77 | PARP1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |