Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | CTRL | P40313 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.38 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690672 | 0.79 | PPID (0.42) | ALDH1A1POLB | |
| SCHEMBL8400709 | 0.75 | FKBP1A (0.41) | ALDH1A1CTSLCTSBPOLBFKBP1A | |
| SCHEMBL4314424 | 0.69 | CTSL (0.40) | ALDH1A1CTSLCTSBTSHRCTSS | |
| SCHEMBL9554848 | 0.69 | FKBP1A (0.55) | ALDH1A1CTSLCTSBPOLBFKBP1A | |
| SCHEMBL9554857 | 0.69 | FKBP1A (0.55) | ALDH1A1CTSLCTSBPOLBFKBP1A | |
| SCHEMBL7356293 | 0.67 | FKBP1A (0.43) | ALDH1A1CTSLCTSBPOLBFKBP1A | |
| SCHEMBL7356298 | 0.67 | FKBP1A (0.43) | ALDH1A1CTSLCTSBPOLBFKBP1A | |
| SCHEMBL21214616 | 0.67 | ALOX5 (0.47) | ALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL6163356 | 0.67 | HDAC8 (0.64) | ALDH1A1FKBP1AMEN1KMT2ATSHR | |
| SCHEMBL6052947 | 0.67 | HDAC8 (0.64) | ALDH1A1FKBP1AMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | claimed |
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |