Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690686 | 0.79 | ALDH1A1 (0.44) | ALDH1A1POLB | |
| SCHEMBL21214616 | 0.70 | ALOX5 (0.47) | PPIDALOX5SMN1; SMN2CYP4F2CYP4A11 | |
| SCHEMBL5496491 | 0.70 | CYP3A4 (0.50) | PPIDPOLB | |
| SCHEMBL5496496 | 0.70 | CYP3A4 (0.50) | PPIDPOLB | |
| SCHEMBL5020123 | 0.67 | PPID (0.58) | PPIDPPARAALDH1A1 | |
| SCHEMBL6791114 | 0.67 | MC4R (0.50) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL6791119 | 0.67 | MC4R (0.50) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7257544 | 0.66 | MME (0.50) | — | |
| SCHEMBL7898943 | 0.66 | NOD2 (0.49) | ALDH1A1POLB | |
| SCHEMBL20355756 | 0.66 | MMP8 (0.49) | PPIDALOX5SMN1; SMN2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |