Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 4/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554912 | 0.83 | RPS6KB1 (0.65) | MAOAMAOBAURKARPS6KB1HDAC3 | |
| SCHEMBL31204891 | 0.83 | RPS6KB1 (0.65) | MAOAMAOBAURKARPS6KB1HDAC3 | |
| SCHEMBL8696115 | 0.81 | DHODH (0.52) | DHODHLMNAGAAHTTNPC1 | |
| SCHEMBL8692447 | 0.79 | KDM4E (0.68) | DHODHLMNAGAAHTTNPC1 | |
| SCHEMBL8693733 | 0.77 | DHODH (0.57) | DHODHGAAHTTNPC1RAB9A | |
| SCHEMBL1632005 | 0.77 | CYP1A2 (0.54) | SMN1; SMN2LMNAGAAHTTNPC1 | |
| SCHEMBL8694084 | 0.75 | DHODH (0.76) | DHODHSMN1; SMN2LMNAGAAHTT | |
| SCHEMBL9842635 | 0.75 | RAB9A (0.68) | DHODHGAAHTTNPC1RAB9A | |
| SCHEMBL29664470 | 0.74 | MAOA (0.56) | MAOAMAOBAURKARPS6KB1HDAC3 | |
| SCHEMBL18394876 | 0.74 | MAOA (0.56) | MAOAMAOBAURKARPS6KB1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043993-C | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1999-07-07 | — | — | CN | disclosed |
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1156455-A | Nonel naphthyridine derivatives and medical composition thereof | YAMANOUCHI PHARMACUEITCAL CO L (JP) | 1997-08-06 | — | — | CN | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |