Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11907830 | 0.85 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1KDM4EP2RY1CYP2C19 | |
| SCHEMBL1577354 | 0.82 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EP2RY1CYP2C19 | |
| SCHEMBL12778358 | 0.79 | POLB (0.38) | ALDH1A1KDM4EMEN1KMT2AAR | |
| SCHEMBL1577617 | 0.76 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1KDM4EP2RY1HTT | |
| SCHEMBL4504278 | 0.75 | CETP (0.49) | L3MBTL1KDM4EMEN1KMT2ACETP | |
| SCHEMBL8691984 | 0.75 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL1577704 | 0.74 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL17980670 | 0.70 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1KDM4ECYP2C19POLB | |
| SCHEMBL9390224 | 0.69 | RAB9A (0.46) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL13321789 | 0.69 | PDK1 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |