Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392372 | 0.75 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1577617 | 0.73 | L3MBTL1 (0.42) | RAB9ANPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9390228 | 0.72 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11907830 | 0.71 | L3MBTL1 (0.39) | RAB9ANPC1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL26054502 | 0.70 | L3MBTL1 (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14848725 | 0.70 | L3MBTL1 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2601270 | 0.70 | NPC1 (0.52) | RAB9ANPC1ALDH1A1MAPTKMT2A | |
| SCHEMBL2494002 | 0.70 | RAB9A (0.59) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8691978 | 0.69 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL29431831 | 0.68 | L3MBTL1 (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026715-A1 | AMIDINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-24 | — | — | WO | disclosed |