Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687585 | 0.79 | ALDH1A1 (0.40) | NUDT1TSHRSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL8692425 | 0.73 | ALDH1A1 (0.35) | TSHRSMN1; SMN2L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL11464975 | 0.73 | NUDT1 (0.67) | NUDT1HRH4TSHRSMN1; SMN2STAT3 | |
| SCHEMBL13884791 | 0.72 | NUDT1 (0.57) | NUDT1HRH4TSHRSMN1; SMN2STAT3 | |
| SCHEMBL4653644 | 0.71 | SMN1; SMN2 (0.50) | HRH4TSHRSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6403623 | 0.71 | ALOX5 (0.45) | NUDT1SMN1; SMN2RAB9ALTA4HMPO | |
| SCHEMBL26660074 | 0.70 | NUDT1 (0.67) | NUDT1HRH4SMN1; SMN2STAT3HTT | |
| SCHEMBL26660073 | 0.70 | NUDT1 (0.67) | NUDT1HRH4SMN1; SMN2STAT3HTT | |
| SCHEMBL11004512 | 0.70 | MAPT (0.46) | SMN1; SMN2STAT3HTTL3MBTL1ALDH1A1 | |
| SCHEMBL6832705 | 0.69 | CDK1 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610302-A | TREATMENT OF DISEASES OF SCALP DERMATITIS | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | claimed |
| EP-0420707-B1 | Compositions to be used to reduce hair-loss and to induce and stimulate its growth, containing derivatives of 2-aminopyrimidine 3-oxide and new compounds derived from 2-aminopyrimidine 3-oxide | OREAL (FR) | 1993-12-15 | — | — | EP | claimed |
| US-5760043-A | USING 2-AMINOPYRIDINE-3-OXIDE | L'OREAL (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5610302-A | TREATMENT OF DISEASES OF SCALP DERMATITIS | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |