Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652471 | 0.74 | NUDT1 (0.45) | NPC1RAB9ASMN1; SMN2NUDT1 | |
| SCHEMBL6401579 | 0.74 | TLR8 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6403131 | 0.74 | TLR8 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6403682 | 0.73 | ALDH1A1 (0.41) | NPC1RAB9ASMN1; SMN2NUDT1 | |
| SCHEMBL10398841 | 0.73 | ALOX5 (0.49) | ALOX5PPARGNPC1RAB9APTGES | |
| SCHEMBL6398146 | 0.71 | CDK1 (0.42) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8692276 | 0.71 | NUDT1 (0.50) | ALOX5RAB9ASMN1; SMN2MPOCDK1 | |
| SCHEMBL11345202 | 0.71 | RPS27 (0.44) | NPC1RAB9ASMN1; SMN2NUDT1 | |
| SCHEMBL7150939 | 0.70 | NPC1 (0.67) | ALOX5PPARGNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6403072 | 0.68 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356271-B1 | 2,4-Diamino-pyrimidine-3-oxide derivatives and their use in the treatment and the prevention of hair drop | OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| US-4973474-A | 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss | L'OREAL (FR) | 1990-11-27 | — | — | US | claimed |
| US-20050049232-A1 | Composition | LINDAU PAR (SE) | 2005-03-03 | — | — | US | disclosed |
| EP-1463483-A1 | NEW COMPOSITION | Ponsus Pharma AB (SE) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003055454-A1 | NEW COMPOSITION | PONSUS PHARMA AB (SE) | 2003-07-10 | — | — | WO | disclosed |
| US-4973474-A | 2,4-diaminopyrimidine 3-oxide derivatives and their use for the treatment and prevention of hair loss | L'OREAL (FR) | 1990-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049232-A1 | Composition | CUTA, LIPG, LIPA | ALOX5 165/4885PPARG 266/4885NPC1 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.