SCHEMBL869302

SCHEMBL869302

CCC(C)(O)[SiH](O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28709849 0.72 TSHR (0.35) TSHR
SCHEMBL28309103 0.70
SCHEMBL21112721 0.68
SCHEMBL15200943 0.66
SCHEMBL17898110 0.62
SCHEMBL16784555 0.60 ALDH1A1 (0.35) TSHR
SCHEMBL4585951 0.58
SCHEMBL21112857 0.57
SCHEMBL19927443 0.57
SCHEMBL511310 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11007161-B1 Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films MORRISON Eric (US) 2021-05-18 US disclosed
US-10596117-B1 Lipoleosomes as carriers for aromatic amide anesthetic compounds MORRISON Eric (US) 2020-03-24 US disclosed
US-10561627-B2 Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films MORRISON Eric (US) 2020-02-18 US disclosed
US-20170296496-A1 Ibuprofen Nanoparticle Carriers Encapsulated with Hermatic Surfactant Films MORRISON Eric (US) 2017-10-19 US disclosed
US-9783760-B2 Conveyor lubricants including emulsion of a lipophilic compound and an emulsifier and/or an anionic surfactant and methods employing them ECOLAB USA INC. (US) 2017-10-10 US disclosed
US-20160184228-A1 UNILAMELLAR NIOSOMES HAVING HIGH Kow PHARMACOLOGICAL COMPOUNDS SOLVATED THEREIN AND A METHOD FOR THE PREPARATION THEREOF MORRISON Eric (US) 2016-06-30 US disclosed
US-9359579-B2 Conveyor lubricants including emulsions and methods employing them ECOLAB USA INC. (US) 2016-06-07 US disclosed
US-20140284176-A1 CONVEYOR LUBRICANTS INCLUDING EMULSION OF A LIPOPHILIC COMPOUND AND AN EMULSIFIER AND/OR AN ANIONIC SURFACTANT AND METHODS EMPLOYING THEM ECOLAB USA INC. (US) 2014-09-25 US disclosed
US-8716200-B2 Conveyor lubricants including emulsion of a lipophilic compound and an emulsifier and/or an anionic surfactant and methods employing them ECOLAB USA INC. (US) 2014-05-06 US disclosed
US-20120073907-A1 CONVEYOR LUBRICANTS INCLUDING EMULSIONS AND METHODS EMPLOYING THEM ECOLAB USA INC. (US) 2012-03-29 US disclosed
US-20080176778-A1 lubricating surfaces used for conveying containers; spraying through nozzles ECOLAB USA INC. 2008-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10561627-B2 Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films S100B, HMOX2, HSPA1B TSHR 4667/4885
US-20170296496-A1 Ibuprofen Nanoparticle Carriers Encapsulated with Hermatic Surfactant Films LIPA, HMOX2, S100B TSHR 4719/4885
US-11007161-B1 Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films AHR, ARNT, SULT2A1 TSHR 4859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.