Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFB | P00751 | 5/20 | 0.57 |
| ▸ | HTR1D | P28221 | 4/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117240 | 0.75 | ADRA2C (0.55) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL8693625 | 0.75 | ATAD2 (0.35) | KCNH2LMNA | |
| Hydrochloric Acid SCHEMBL8111465 | 0.74 | ADRA2C (0.53) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL11187565 | 0.74 | HTR1D (0.76) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL4760243 | 0.74 | HTR1D (1.00) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| Hydrochloric Acid SCHEMBL29384552 | 0.72 | HTR1D (0.97) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL10979251 | 0.71 | HTR1D (0.71) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL6585037 | 0.71 | HTR1D (0.55) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| SCHEMBL7742097 | 0.71 | ADRA2A (0.55) | CFBHTR1DADRA2CADRA1AKCNH2 | |
| Hydrochloric Acid SCHEMBL10973842 | 0.70 | HTR1D (0.69) | CFBHTR1DADRA2CADRA1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804587-A | 6-(2-imidazolinylamino) quinolines useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-08 | — | — | US | disclosed |