Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693621 | 0.75 | CFB (0.57) | LMNAKCNH2 | |
| SCHEMBL8117244 | 0.73 | SLC40A1 (0.44) | SMN1; SMN2ALDH1A1LMNAHTTNPC1 | |
| Hydrochloric Acid SCHEMBL8111469 | 0.72 | SLC40A1 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTNPC1 | |
| SCHEMBL862236 | 0.70 | NPC1 (0.54) | ATAD2SMN1; SMN2NUDT1ALDH1A1HTT | |
| SCHEMBL8692881 | 0.70 | NR4A2 (0.47) | ATAD2SMN1; SMN2NUDT1ALDH1A1LMNA | |
| SCHEMBL29511693 | 0.70 | NR4A2 (0.47) | ATAD2SMN1; SMN2NUDT1ALDH1A1LMNA | |
| SCHEMBL7742100 | 0.68 | L3MBTL1 (0.38) | ALDH1A1LMNANPC1HSP90AA1L3MBTL1 | |
| SCHEMBL20123930 | 0.68 | ALDH1A1 (0.43) | ATAD2SMN1; SMN2NUDT1RIPK2ALDH1A1 | |
| SCHEMBL7743448 | 0.66 | SLC40A1 (0.40) | ALDH1A1NPC1HSP90AA1L3MBTL1 | |
| SCHEMBL7742996 | 0.66 | DDB1 (0.54) | ALDH1A1HTTNPC1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804587-A | 6-(2-imidazolinylamino) quinolines useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-08 | — | — | US | disclosed |