Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117248 | 0.75 | L3MBTL1 (0.41) | SMN1; SMN2ALDH1A1LMNAHTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8111472 | 0.74 | L3MBTL1 (0.40) | SMN1; SMN2ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL8693621 | 0.72 | CFB (0.57) | LMNAKMT2ABLM | |
| SCHEMBL8693625 | 0.70 | ATAD2 (0.35) | ATAD2CYP1A2CYP1B1NUDT1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8690527 | 0.70 | KDM4E (0.36) | ALDH1A1LMNAHTTL3MBTL1NPC1 | |
| SCHEMBL10979249 | 0.69 | MEN1 (0.30) | ALDH1A1MAPTKMT2A | |
| SCHEMBL8117265 | 0.69 | NPC1 (0.48) | CYP1A2SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL7743450 | 0.68 | LRRK2 (0.36) | ALDH1A1L3MBTL1NPC1HSP90AA1MAPT | |
| SCHEMBL862236 | 0.68 | NPC1 (0.54) | ATAD2CYP1A2CYP1B1NUDT1SMN1; SMN2 | |
| SCHEMBL29511693 | 0.67 | NR4A2 (0.47) | ATAD2CYP1A2CYP1B1NUDT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804587-A | 6-(2-imidazolinylamino) quinolines useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-08 | — | — | US | disclosed |