Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 4/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694583 | 0.86 | LMNA (0.39) | FPR1FPR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8693539 | 0.84 | FPR1 (0.37) | FPR1FPR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8690998 | 0.82 | CNR2 (0.38) | FPR1FPR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8693681 | 0.82 | FPR1 (0.40) | FPR1FPR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL8691445 | 0.81 | CYP2C19 (0.48) | FPR1FPR2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9034552 | 0.76 | HPGD (0.48) | ALDH1A1KMT2AHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL8692841 | 0.74 | HRH1 (0.36) | FPR1FPR2HSP90AA1HSP90B1SMN1; SMN2 | |
| SCHEMBL12499839 | 0.73 | LMNA (0.43) | ALDH1A1KMT2AHSP90AA1GAAMAPT | |
| SCHEMBL12499851 | 0.72 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8693926 | 0.72 | HRH1 (0.35) | HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |