Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MYOC | Q99972 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.89 | HSPB1 (0.79) | HSD17B10ACHEHSPB1HTTKMT2A | |
| SCHEMBL11689190 | 0.89 | HSPB1 (0.79) | HSD17B10ACHEHSPB1HTTKMT2A | |
| SCHEMBL2011179 | 0.89 | HSPB1 (0.79) | HSD17B10ACHEHSPB1HTTKMT2A | |
| SCHEMBL9183872 | 0.89 | HSPB1 (0.79) | HSD17B10ACHEHSPB1HTTKMT2A | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 | 0.87 | HSPB1 (0.76) | HSPB1HTTKMT2AMEN1MAPK1 | |
| 4-Nitrotoluene SCHEMBL2484690 | 0.87 | ACHE (1.00) | HSD17B10ACHEKMT2AMAPK1MAPT | |
| 4-Nitrotoluene SCHEMBL73252 | 0.87 | ACHE (1.00) | HSD17B10ACHEKMT2AMAPK1MAPT | |
| SCHEMBL1323759 | 0.86 | HSPB1 (0.59) | HSD17B10ACHEHSPB1HTTKMT2A | |
| 4-Nitrotoluene SCHEMBL28077886 | 0.84 | ALDH1A1 (0.60) | HSD17B10ACHEHSPB1HTTKMT2A | |
| 4-Nitrotoluene SCHEMBL9402408 | 0.84 | ACHE (0.95) | HSD17B10ACHEKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707816-A | Pyrazole hydrazide derivative containing diphenyl ether unit as well as preparation method and application thereof | 江苏海洋大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-118359503-A | Synthesis method of copper-catalyzed diaryl ether promoted by visible light | 新疆大学 | 2024-07-19 | — | — | CN | disclosed |
| US-9751897-B1 | Derivatives of Bodipy | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-09-05 | — | — | US | disclosed |
| WO-2017139689-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | WO | disclosed |
| US-20170233414-A1 | DERIVATIVES OF BODIPY | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-08-17 | — | — | US | disclosed |
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365513-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9196843-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9196843-B2 | Fullerene derivative, and method of preparing the same | RICOH COMPANY, LTD. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9096528-B2 | 2-aminonicotinic acid ester derivative and bactericide containing same as active ingredient | AGRO-KANESHO CO., LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-5750789-A | FROM CORRESPONDING DIAMINE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5498687-A | Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5444165-A | Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-08-22 | — | — | US | disclosed |
| US-5326881-A | Polymers with good heat resistance, good flexibility and low water absorption | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0595230-A1 | Unsaturated imide compounds containing alicyclic structure | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5132423-A | Nucleophilic substitution reaction of alkali hydroxy- or mercaptoaromatic compound and heterocyclic substituted imide | GENERAL ELECTRIC COMPANY (US) | 1992-07-21 | — | — | US | disclosed |
| US-5116975-A | Bis(guanidinium)alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| US-5081298-A | Bis(pentaalkylguanidinium) alkane salts as phase transfer catalysts | GENERAL ELECTRIC COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| US-4329365-A | DIPHENYL ETHERS | BURROUGHS WELLCOME CO. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4042603-A | SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE | UBE INDUSTRIES, LTD. (JA) | 1977-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233414-A1 | DERIVATIVES OF BODIPY | NPC1L1, NPC1, ABCB4 | HSD17B10 1249/4885ACHE 4733/4885HSPB1 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.