Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.36 |
| ▸ | ITGAV | P06756 | 14/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694013 | 0.81 | RXFP1 (0.39) | RXFP1LMNAMAPTHTT | |
| SCHEMBL8693773 | 0.66 | RXFP1 (0.40) | RXFP1LMNAMAPTHTT | |
| SCHEMBL8429158 | 0.64 | ITGB3 (0.44) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8538079 | 0.62 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7753126 | 0.61 | ADRA2A (0.58) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8696196 | 0.61 | ITGB3 (0.48) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL8541005 | 0.61 | ITGB3 (0.50) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| Hydrochloric Acid SCHEMBL7562956 | 0.60 | ADRA2A (0.57) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL2839861 | 0.60 | ITGB3 (0.55) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL1036359 | 0.59 | ADRA2A (0.78) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843906-A | Meta-substituted phenylene sulphonamide derivatives | G. D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | disclosed |