Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | IDH2 | P48735 | 1/20 | 0.30 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693773 | 0.85 | RXFP1 (0.40) | RXFP1F2ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL8696189 | 0.81 | ITGB3 (0.36) | RXFP1HTTMAPTLMNA | |
| SCHEMBL8429456 | 0.72 | RXFP1 (0.44) | RXFP1ALDH1A1CYP3A4CYP2C9GRIK1 | |
| SCHEMBL8429164 | 0.70 | RXFP1 (0.36) | RXFP1F2HTTMAPTMEN1 | |
| SCHEMBL8696800 | 0.64 | LMNA (0.33) | ALDH1A1HPGDHTTMAPTKMT2A | |
| SCHEMBL8698654 | 0.63 | PTGER1 (0.34) | MEN1KMT2ACA1CA2 | |
| SCHEMBL8429105 | 0.62 | PLAU (0.38) | RXFP1ALDH1A1CYP3A4CYP2C9HTT | |
| SCHEMBL8432256 | 0.62 | L3MBTL1 (0.38) | ALDH1A1HPGDHTTMAPTMEN1 | |
| Bicarbonate SCHEMBL7469511 | 0.61 | MAPT (0.65) | ALDH1A1HTTMAPTMEN1RAB9A | |
| SCHEMBL16450915 | 0.60 | HDAC8 (0.53) | RXFP1ALDH1A1HTTMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843906-A | Meta-substituted phenylene sulphonamide derivatives | G. D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | disclosed |