Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696240 | 1.00 | MMP2 (0.42) | MMP2MMP13CTSBCAPN1CTSS | |
| SCHEMBL8696250 | 1.00 | MMP2 (0.42) | MMP2MMP13CTSBCAPN1CTSS | |
| SCHEMBL7413210 | 0.84 | CTSL (0.57) | MMP2MMP13CTSBCTSSCTSL | |
| SCHEMBL7362208 | 0.84 | CTSL (0.57) | MMP2MMP13CTSBCTSSCTSL | |
| SCHEMBL7362205 | 0.84 | CTSL (0.57) | MMP2MMP13CTSBCTSSCTSL | |
| SCHEMBL7358323 | 0.81 | CTSL (0.62) | CTSBCTSSCTSLCTSKCTSH | |
| SCHEMBL7358322 | 0.81 | CTSL (0.62) | CTSBCTSSCTSLCTSKCTSH | |
| SCHEMBL7358325 | 0.81 | CTSL (0.62) | CTSBCTSSCTSLCTSKCTSH | |
| SCHEMBL7546891 | 0.81 | CTSS (0.60) | CTSBCTSSCTSLCTSCALDH1A1 | |
| SCHEMBL8690335 | 0.80 | CTSS (0.46) | CTSBCTSSCTSLCTSKCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |