Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 3/20 | 0.37 |
| ▸ | REN | P00797 | 10/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413216 | 0.85 | CTSK (0.42) | CTSBCTSLCTSS | |
| SCHEMBL7358329 | 0.82 | CTSK (0.46) | CTSBCTSLCTSS | |
| SCHEMBL8690341 | 0.75 | SSTR4 (0.39) | SSTR4CTSBPSMB5CTSLALDH1A1 | |
| SCHEMBL8696240 | 0.66 | MMP2 (0.42) | CTSBCAPN1CTSLCTSSALDH1A1 | |
| SCHEMBL8696245 | 0.66 | MMP2 (0.42) | CTSBCAPN1CTSLCTSSALDH1A1 | |
| SCHEMBL8696250 | 0.66 | MMP2 (0.42) | CTSBCAPN1CTSLCTSSALDH1A1 | |
| SCHEMBL7412508 | 0.62 | CTSB (0.55) | CTSBCTSLCTSS | |
| SCHEMBL7412506 | 0.62 | CTSB (0.55) | CTSBCTSLCTSS | |
| SCHEMBL8156320 | 0.62 | REN (0.42) | SSTR4RENCTSBCTSLCTSS | |
| SCHEMBL7411057 | 0.62 | CTSC (0.37) | SSTR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776718-A | Reversible protease inhibitors | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |