Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700366 | 0.85 | KDM4E (0.39) | ERCC5FEN1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL8697492 | 0.83 | KMT2A (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8700373 | 0.83 | AR (0.40) | TP53ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL8702479 | 0.83 | KMT2A (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL8696621 | 0.82 | G6PD (0.41) | ALDH1A1SMN1; SMN2CES2CES1LMNA | |
| SCHEMBL8702066 | 0.82 | KMT2A (0.32) | ALDH1A1KMT2A | |
| SCHEMBL8700342 | 0.80 | MAOB (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL8697830 | 0.80 | KMT2A (0.41) | ALDH1A1SMN1; SMN2CES2CES1KMT2A | |
| SCHEMBL8697105 | 0.79 | MMP2 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2CES2 | |
| SCHEMBL8700404 | 0.78 | CES2 (0.36) | ALDH1A1TAS1R3TAS1R1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003478-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |
| WO-1998003479-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |