Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700366 | 0.83 | KDM4E (0.39) | KMT2AMEN1GAAPOLBNPC1 | |
| SCHEMBL8696907 | 0.83 | ERCC5 (0.38) | KMT2AHPGDPOLBNPC1RAB9A | |
| SCHEMBL8700373 | 0.81 | AR (0.40) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL8702479 | 0.81 | KMT2A (0.42) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL8702066 | 0.80 | KMT2A (0.32) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8697830 | 0.78 | KMT2A (0.41) | KMT2AMEN1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8697105 | 0.77 | MMP2 (0.41) | KMT2AMEN1GAAHPGDPOLB | |
| SCHEMBL8696621 | 0.76 | G6PD (0.41) | KMT2AMEN1GAAMAPTSMN1; SMN2 | |
| SCHEMBL8700404 | 0.76 | CES2 (0.36) | KMT2AGAANPC1RAB9AALDH1A1 | |
| SCHEMBL8702048 | 0.76 | MMP2 (0.40) | KMT2AMEN1POLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998003479-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |
| WO-1998003478-A1 | NITRONE DERIVATIVES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-01-29 | — | — | WO | disclosed |