Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072913 | 0.79 | GRIA1 (0.49) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10492182 | 0.74 | GRIA1 (0.46) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7912335 | 0.71 | CYP19A1 (0.69) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8409596 | 0.70 | ALDH1A1 (0.50) | GRIA1GRIA2GRIA3GRIA4ALDH1A1 | |
| SCHEMBL8409653 | 0.69 | CACNA1C (0.47) | TSHRALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27868663 | 0.69 | TUBB4A (0.43) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8595591 | 0.67 | CTSV (0.46) | ALDH1A1MEN1MAPTKMT2AHTT | |
| SCHEMBL30917347 | 0.66 | CYP19A1 (0.60) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL317330 | 0.66 | CYP19A1 (0.60) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL12722533 | 0.65 | MAPT (0.59) | TSHRGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |