Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446810 | 0.87 | ADRB2 (0.37) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL9646606 | 0.81 | ALDH1A1 (0.40) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL84576 | 0.77 | P2RX3 (0.41) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL9446866 | 0.75 | ADRB3 (0.64) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL8696649 | 0.74 | CPB2 (0.40) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL10493929 | 0.72 | ADRB2 (0.53) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL10493809 | 0.72 | ADRB1 (0.42) | ADRB2ADRB1CYP3A4MAPK1ADRB3 | |
| SCHEMBL9649455 | 0.71 | CSNK1A1 (0.37) | KDM4EHTTCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL9648469 | 0.71 | HTT (0.37) | KDM4EHTTCSNK1A1CLK4ALDH1A1 | |
| SCHEMBL23888650 | 0.71 | CSNK1A1 (0.41) | KDM4EHTTCSNK1A1CLK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |
| US-5216170-A | Promoters of livestock; treatment of obesity | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0244728-B1 | USE OF HETEROARYLETHYL AMINES TO STIMULATE ANIMAL GROWTH, HETEROARYLETHYL AMINES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| US-5028617-A | Heteroarylethanol-pyridylalkylamines for controlling animal growth | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| EP-0379928-A2 | Aryl- and heteroarylethanol-pyridylalkylamines, process for their preparation and their use as performance stimulators by animals and as anti-adipositas agent | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4863939-A | Heteroarylethylamine as production promoters in livestock | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0256420-A2 | Heteroarylethyl amines, process for their synthesis and their use in the promotion of animal performance | BAYER AG (DE) | 1988-02-24 | — | — | EP | disclosed |
| EP-0244728-A2 | Use of heteroarylethyl amines to stimulate animal growth, heteroarylethyl amines and process for their preparation | BAYER AG (DE) | 1987-11-11 | — | — | EP | disclosed |