Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704175 | 0.89 | CYP2A6 (0.34) | CYP19A1CYP2A6PRKCQPRKCDCYP11B1 | |
| SCHEMBL8697485 | 0.81 | CYP11B1 (0.34) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL8696314 | 0.78 | CYP19A1 (0.41) | CYP19A1CYP2A6PRKCQPRKCDMETAP2 | |
| SCHEMBL8696579 | 0.74 | MAOB (0.46) | METAP2MKNK1MAOAMAOBALOX5 | |
| SCHEMBL8698524 | 0.69 | FLT1 (0.33) | CYP11B1CYP11B2KDM4EALDH1A1MAPT | |
| SCHEMBL24621094 | 0.69 | CYP19A1 (0.42) | CYP19A1METAP2KDM4ETDP1NPC1 | |
| SCHEMBL8702186 | 0.67 | CYP19A1 (0.47) | CYP19A1CYP2A6KDM4EALDH1A1NPC1 | |
| SCHEMBL8698118 | 0.66 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL8700537 | 0.66 | CYP19A1 (0.47) | CYP19A1CYP2A6MAOAMAOBMAPT | |
| SCHEMBL8700378 | 0.65 | MAOB (0.46) | CYP19A1METAP2MAOAMAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |