Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787750 | 0.87 | PEPD (0.56) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL7140644 | 0.79 | MAPT (0.50) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL11445693 | 0.78 | PEPD (0.48) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL7538988 | 0.76 | LMNA (0.58) | ALDH1A1MAPTGAAMEN1LMNA | |
| SCHEMBL6938372 | 0.76 | PEPD (0.64) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL3690365 | 0.73 | MAPT (0.59) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL2910974 | 0.71 | ALDH1A1 (0.61) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL2891974 | 0.71 | NPC1 (0.61) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL9413738 | 0.71 | PEPD (0.46) | PEPDALDH1A1NPC1MAPTGAA | |
| SCHEMBL5523767 | 0.71 | CYP1A2 (0.58) | PEPDALDH1A1NPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747489-A | Arylalkyl-thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |