Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690365 | 0.85 | MAPT (0.59) | MAPTGAAGFERDDX3XPEPD | |
| SCHEMBL28332617 | 0.82 | GPR35 (0.50) | MAPTGAADDX3XALDH1A1NPC1 | |
| SCHEMBL7391700 | 0.80 | KMT2A (0.40) | DDX3XALDH1A1GPR35KMT2AMEN1 | |
| SCHEMBL839236 | 0.80 | ALDH1A1 (0.63) | MAPTALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL1356066 | 0.79 | CA1 (0.59) | MAPTGAACA1CA2KMT2A | |
| SCHEMBL8698243 | 0.79 | PEPD (0.46) | MAPTGAAGFERPEPDKIF11 | |
| SCHEMBL5544315 | 0.78 | MAPT (0.52) | MAPTGAAGFERDDX3XPEPD | |
| SCHEMBL3185695 | 0.78 | KMT2A (0.66) | MAPTGAAGFERPEPDALDH1A1 | |
| SCHEMBL33716 | 0.78 | DDX3X (0.74) | MAPTGAAGFERDDX3XPEPD | |
| SCHEMBL7564141 | 0.78 | GAA (0.52) | MAPTGAAGFERDDX3XPEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189929-B1 | FACTOR VIIA INHIBITORS | AVENTIS PHARMA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6500803-B1 | Factor VIIa inhibitors | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |
| US-5614498-A | OLIGOPEPTIDES, BRONCHDILATORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0329169-A1 | N-(lower alkyl)-2-(3'-ureidobenzyl)-pyrrolidines | SYNTEX (U.S.A.) INC. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4826869-A | GLAUCOMA | SYNTEX (U.S.A.) INC. (US) | 1989-05-02 | — | — | US | disclosed |