Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432521 | 0.81 | ABCB11 (0.41) | CA1CA2LMNAITGB3ITGAV | |
| SCHEMBL8696220 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1GAACA1CA2 | |
| SCHEMBL8428908 | 0.79 | ITGB3 (0.38) | KDM4EALDH1A1CA1CA2MAPT | |
| SCHEMBL8429321 | 0.79 | ITGB3 (0.38) | CA1CA2LMNAITGB3ITGAV | |
| SCHEMBL8432903 | 0.78 | ITGB3 (0.39) | CA1CA2LMNAITGB3ITGAV | |
| SCHEMBL8429187 | 0.78 | ITGB3 (0.37) | CA1CA2ITGB3ITGAVITGA2B | |
| SCHEMBL8431244 | 0.77 | ITGB3 (0.37) | CA1CA2ITGB3ITGAVITGA2B | |
| SCHEMBL8432815 | 0.76 | ITGB3 (0.40) | ALDH1A1LMNAMEN1KMT2AITGB3 | |
| SCHEMBL8429208 | 0.75 | SIRT1 (0.37) | CA1CA2ITGB3ITGAVITGA2B | |
| SCHEMBL8530525 | 0.75 | ABCB11 (0.54) | CA1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843906-A | Meta-substituted phenylene sulphonamide derivatives | G. D. SEARLE & CO. (US) | 1998-12-01 | — | — | US | disclosed |