Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540280 | 0.82 | TBXAS1 (0.46) | TBXAS1CYP19A1F2ENPP2PREP | |
| SCHEMBL8696892 | 0.78 | CYP19A1 (0.48) | TBXAS1CYP19A1PKMPREP | |
| SCHEMBL8699553 | 0.77 | PKM (0.52) | TBXAS1CYP19A1PKM | |
| SCHEMBL8545595 | 0.76 | PKM (0.59) | TBXAS1PKM | |
| Hydrochloric Acid SCHEMBL8540290 | 0.75 | PKM (0.59) | TBXAS1PKM | |
| SCHEMBL8699079 | 0.75 | F2 (0.40) | F2PREP | |
| SCHEMBL8701243 | 0.74 | NPC1 (0.62) | TBXAS1PKM | |
| SCHEMBL8699085 | 0.73 | PKM (0.49) | TBXAS1CYP19A1PKMTP53 | |
| SCHEMBL7296025 | 0.72 | F2 (0.55) | F2PREP | |
| SCHEMBL6171266 | 0.71 | PKM (0.45) | TBXAS1CYP19A1PKMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |