Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699080 | 0.82 | TBXAS1 (0.47) | TBXAS1CYP19A1ENPP2F2PREP | |
| SCHEMBL8545098 | 0.78 | SIGMAR1 (0.55) | TBXAS1CYP19A1 | |
| SCHEMBL8540527 | 0.77 | HDAC3 (0.52) | TBXAS1CYP19A1NAMPTFAAH | |
| SCHEMBL22051980 | 0.75 | KEAP1 (0.53) | P2RX7F2PREPFAAH | |
| SCHEMBL8545335 | 0.75 | HDAC3 (0.54) | TBXAS1CYP19A1FAAH | |
| SCHEMBL8540312 | 0.73 | GRIN2B (0.55) | TBXAS1FAAH | |
| SCHEMBL8538696 | 0.72 | FAAH (0.50) | TBXAS1FAAH | |
| SCHEMBL8545247 | 0.71 | USP7 (0.52) | TBXAS1CYP19A1RAB9A | |
| SCHEMBL6492368 | 0.70 | GRIN2B (0.56) | NAMPT | |
| SCHEMBL8541762 | 0.70 | TBXAS1 (0.58) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |