Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL2359624 | 0.87 | HTT (0.42) | IDO1ALDH1A1BLM | |
| SCHEMBL1087686 | 0.83 | GID4 (0.43) | GID4IDO1ADRA2AADRA1ACYP2D6 | |
| SCHEMBL13309033 | 0.79 | MAOA (0.43) | GID4IDO1ADRA2AADRA1ACYP2D6 | |
| SCHEMBL13309017 | 0.76 | GID4 (0.42) | GID4IDO1ADRA2AADRA1ACYP2D6 | |
| SCHEMBL13309038 | 0.76 | ORAI1 (0.44) | GID4IDO1ADRA2AADRA1ACYP2D6 | |
| SCHEMBL13309026 | 0.76 | ADRA2A (0.43) | GID4ADRA2AADRA1AOPRM1 | |
| SCHEMBL21249029 | 0.75 | PDE7A (0.41) | GID4IDO1ADRA2AADRA1ACYP2D6 | |
| SCHEMBL829452 | 0.75 | TSHR (0.43) | ADRA2AADRA1A | |
| SCHEMBL10836480 | 0.74 | TLR4 (0.38) | GID4ADRA2AADRA1A | |
| SCHEMBL1099599 | 0.73 | ADRA1A (0.43) | GID4IDO1ADRA2AADRA1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005651-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYL QUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |