Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699251 | 0.93 | HCRTR1 (0.41) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL2846412 | 0.80 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL3128179 | 0.79 | TLR2 (0.46) | ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL2556550 | 0.78 | L3MBTL1 (0.59) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL28519240 | 0.78 | L3MBTL1 (0.46) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL30594480 | 0.78 | KMT2A (0.48) | ALDH1A1L3MBTL1MAPTNPSR1KDM4E | |
| 1,2-Diethoxybenzene SCHEMBL28074336 | 0.77 | L3MBTL1 (0.57) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL28002827 | 0.76 | ALDH1A1 (0.52) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 | |
| SCHEMBL7019519 | 0.76 | MAPT (0.55) | L3MBTL1MAPTTDP1GAA | |
| SCHEMBL4180647 | 0.75 | LMNA (0.48) | HCRTR1ALDH1A1L3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008837-A1 | PHENYLBUTANOL DERIVATIVES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FARMACON, INC. (US) | 1998-03-05 | — | — | WO | disclosed |