Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702327 | 0.79 | PPARA (0.61) | PPARAPPARGCYP4F2CYP4A11MAOB | |
| SCHEMBL8698655 | 0.77 | IDO1 (0.39) | PPARAPPARGBTN3A1IDO1AGXT | |
| SCHEMBL8701740 | 0.76 | IDO1 (0.38) | PPARAPPARGBTN3A1IDO1AGXT | |
| SCHEMBL15778630 | 0.75 | IDO1 (0.60) | IDO1AGXTMAOB | |
| SCHEMBL8715771 | 0.75 | IDO1 (0.39) | PPARAPPARGBTN3A1IDO1AGXT | |
| SCHEMBL8699744 | 0.73 | BTN3A1 (0.36) | PPARAPPARGBTN3A1IDO1AGXT | |
| SCHEMBL906701 | 0.72 | CA2 (0.47) | BTN3A1ALDH1A1 | |
| SCHEMBL11942311 | 0.72 | IDO1 (0.38) | IDO1AGXT | |
| SCHEMBL8699534 | 0.71 | PPARA (0.57) | PPARAPPARGALDH1A1MAOB | |
| SCHEMBL20201343 | 0.71 | CYP2C19 (0.37) | BTN3A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485026-A2 | Antimanic phenoxymethylene bisphosphonate derivatives | MERCK SHARP & DOHME LTD. (GB) | 1992-05-13 | — | — | EP | disclosed |