Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630823 | 0.86 | KDM4E (0.50) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8700566 | 0.85 | KDM4E (0.55) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8705825 | 0.84 | KDM4E (0.48) | KDM4ENPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL8705791 | 0.84 | KDM4E (0.45) | SLC6A9KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8446533 | 0.79 | SLC9A1 (0.64) | SLC9A1 | |
| SCHEMBL8700610 | 0.79 | SLC9A1 (0.49) | KDM4ESLC9A1ALDH1A1TSHRHPGD | |
| SCHEMBL8703757 | 0.76 | PKM (0.40) | KDM4ESMN1; SMN2SLC9A1ALDH1A1TSHR | |
| SCHEMBL8581950 | 0.75 | ALDH1A1 (0.40) | KDM4ESMN1; SMN2SLC9A1ALDH1A1TSHR | |
| SCHEMBL8585515 | 0.74 | SCN9A (0.43) | SLC9A1ALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL8701815 | 0.74 | HTT (0.43) | SLC9A1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |