Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739786 | 0.80 | ENPP3 (0.34) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL9739192 | 0.80 | ENPP3 (0.34) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL6099839 | 0.77 | THRB (0.32) | SLC6A3 | |
| SCHEMBL8697053 | 0.77 | ENPP3 (0.35) | HPGDENPP3ENPP1SLC6A3ALPL | |
| SCHEMBL10589667 | 0.74 | MAPT (0.34) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL9738766 | 0.72 | ENPP3 (0.31) | MAPTRAB9ANPC1CASP3SMN1; SMN2 | |
| SCHEMBL9325335 | 0.72 | ALDH1A1 (0.47) | MAPTRAB9ASMN1; SMN2NR1H4HPGD | |
| SCHEMBL13898850 | 0.72 | PTGS2 (0.31) | — | |
| SCHEMBL4653029 | 0.72 | ALDH1A1 (0.37) | MAPTRAB9ANPC1KMT2AMAPK1 | |
| SCHEMBL8697678 | 0.71 | KMT2A (0.35) | MAPTRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |