Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8705376 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8705336 | 0.88 | ALDH1A1 (0.37) | ALDH1A1NPSR1 | |
| SCHEMBL8706344 | 0.87 | SYK (0.39) | KDM4EALDH1A1SYKOPRK1 | |
| SCHEMBL8705825 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8630823 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8700295 | 0.82 | SLC9A1 (0.58) | — | |
| SCHEMBL8704819 | 0.78 | BTK (0.39) | KDM4EALDH1A1OPRK1NPC1RAB9A | |
| SCHEMBL9259719 | 0.75 | CKS1B (0.41) | OPRK1 | |
| SCHEMBL8699639 | 0.73 | SLC9A1 (0.49) | — | |
| SCHEMBL8703772 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1OPRK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |